Early Structural Changes in Mitochondria in Response to Acute Reductions in Capillary Flow

  • David R. Antonenko
  • William J. Gibson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


Swelling of cells after prolonged shock whether septic or hemorrhagic is well accepted. Evidence for cell edema reflected by swelling of mitochondria and sarcoplasmic reticulum is not evident before the late stages of shock (6). However, reductions in cell membrane potential implying interference with the membrane pump and consequent cell edema occur very early after an acute hemorrhage (4).


Mean Arterial Pressure Sarcoplasmic Reticulum Hemorrhagic Shock Unit Cell Volume Intermembranous Space 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • David R. Antonenko
    • 1
  • William J. Gibson
    • 1
  1. 1.Department of Surgery, Royal Alexandra Hospital and Surgical Medical Research InstituteUniversity of AlbertaEdmontonCanada

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