Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes

  • Jochen Duhm
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


This report is divided into two parts. The first is concerned with the binding of 2,3-diphosphoglycerate (DPG) to deoxy- and oxyhemoglobin in the absence and presence of CO2 under conditions comparable to those prevailing in intact erythrocytes. In the second part an attempt is made to analyze the mechanism by which glycolysis is inhibited in erythrocytes containing elevated concentrations of DPG.


Human Erythrocyte Oxygen Affinity Glycolytic Rate Linkage Equation Intact Erythrocyte 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Jochen Duhm
    • 1
  1. 1.Physiologisches InstitutUniversität MünchenMünchenGermany

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