Carbonate: Key to Transferrin Chemistry
Transferrin, the serum iron transport protein, has three important functions. First, to sequester iron; second, to transport it in a form that is nontoxic and unavailable to the nonspecific complexing agents of serum; and third, to release iron to specific receptor sites on cell membranes. The chemistry of transferrin is a reflection of these physiological functions. Current topics in transferrin research are presented in the proceedings of the recent European Biology Organization Workshop on Iron Proteins (1).
KeywordsBinary Complex Metal Binding Site Iron Release Iron Removal Apparent Dissociation Constant
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