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Heme Interactions in Pseudomonas Cytochrome Oxidase

  • David C. Wharton
  • Kristina Hill
  • Quentin H. Gibson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 74)

Abstract

Pseudomonas cytochrome oxidase (ferrocytochrome c2:O2 oxido-reductase, EC 1.9.3.2) functions as a terminal electron carrier in the bacterium Pseudomonas aeruginosa. The oxidase can donate electrons either to molecular oxygen or to nitrite although it appears that in situ it is intended to react with nitrite rather than 02 since the enzyme is only synthesized when the organism is grown anaerobically in the presence of nitrate or nitrite. However, since Pseudomonas cytochrome oxidase can catalyze the reduction of O2 to H2O (a four-electron transfer) it bears some similarity functionally to the cytochrome c oxidase of the mitochondrial respiratory chain.

Keywords

Oxidase Activity Cytochrome Oxidase Slow Phase Mitochondrial Cytochrome Absorbance Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • David C. Wharton
    • 1
    • 2
  • Kristina Hill
    • 1
    • 2
  • Quentin H. Gibson
    • 1
    • 2
  1. 1.Department of Biochemistry, Health Science CenterThe University of TexasSan AntonioUSA
  2. 2.Section of Biochemistry, Cell and Molecular BiologyCornell UniversityIthacaUSA

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