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Kinins pp 301-314 | Cite as

Cardiovascular and Respiratory Reflexes Elicited by Bradykinin Acting on Receptor Sites (K & P) in the Muscular Circulatory Area

  • G. Tallarida
  • F. Baldoni
  • G. Peruzzi
  • A. Semprini
  • M. Sangiorgi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 70)

Abstract

It is well known that there are sensory receptors in the heart and lungs which, excited by chemical agents, cause inhibitory reflexes consisting of fall in arterial blood pressure and heart rate accompanied by changes in respiratory movements (Dawes and Comroe, 1954; Linden, 1973). There is also agreement that peripheral blood vessels are supplied with sensory nerve fibres, subserving pain-sensibility, peculiarly sensitive to stimuli of chemical kind. The stimulation of these algoceptive afferents in the muscular circulatory area induces a series of excitatory reflex responses consisting of behavioral agitation, vocalization, rise in blood pressure, tachycardia and hypertachypnea (Moore et al. 1934; Lim, 1960; Guzman et al. 1962).

Keywords

Reflex Response Carotid Sinus Anesthetize Animal Hypertonic Solution Depressor Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • G. Tallarida
    • 1
  • F. Baldoni
    • 1
  • G. Peruzzi
    • 1
  • A. Semprini
    • 1
  • M. Sangiorgi
    • 1
  1. 1.Instituto di I Clinica Medica and Cattedra di I Semeiotica MedicaUniversity of RomeRomeItaly

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