Mechanisms of Transport for the Uptake and Release of Biogenic Amines in Nerve Endings

  • Donald F. Bogdanski
Part of the Advances in Experimental Medicine and Biology book series (AEMB)


Reports on the amine transport mechanism located at the plasma membrane of nerve endings have been extensively reviewed for general characteristics 30, 31, 49, and for the effects of electrolytes 46. The nerve ending is uncommon, or unique in the sense that the product of secretion is recaptured almost immediately by the secretory organ. Transport, therefore, may be a bidirectional phenomenon in nerve endings. As a result of investigations, a synaptic sub-unit is envisaged in which electrolytes play an important role in the mobilization of amine as well as for transport in both directions.


ATPase Activity Synaptic Transmission Biogenic Amine Nerve Ending Outward Transport 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Donald F. Bogdanski
    • 1
  1. 1.Section on Biochemical Pharmacology, Hypertension-Endocrine BranchNational Heart and Lung Institute, National Institutes of HealthBethesdaUSA

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