Transport of Taurine in the Central Nervous System

  • S. S. Oja
  • P. Kontro
  • P. Lähdesmäki
Part of the Advances in Experimental Medicine and Biology book series (AEMB)

Abstract

Taurine, 2-aminoethanesulphonic acid, is present in brain tissue in millimolar concentrations44; however, taurine levels show considerable differences in different mammalian species38 and at different developmental stages37. The physiological role of taurine, apart from its conjugation with bile acids, is virtually obscure. However, more and more attention has been paid to its possible function in electrically excitable tissues, such as brain, retina, heart or muscle. Taurine inhibits the spontaneous firing of some central synapses with a potency equal to that of γ-aminobutyric acid8,17 and affects the excitability of cardiac muscle46, 58. Some authors are therefore inclined to consider taurine one of the inhibitory neurotransmitters10, 29, 42

Keywords

Manifold Glycine Cysteine Cyanide Epinephrine 

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • S. S. Oja
    • 1
    • 2
  • P. Kontro
    • 1
    • 2
  • P. Lähdesmäki
    • 1
    • 2
  1. 1.Institute of Biomedical SciencesUniversity of TampereFinland
  2. 2.Department of BiochemistryUniversity of OuluFinland

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