Penetration of Proteins in the Central Nervous System

  • Emanuel Levin
  • Carlos E. Tradatti
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 69)


The subject of penetration of protein derivatives and other macromolecules into the CNS has no extensive literature; until recently it was assumed that such entry was practically negligible. The well known barrier phenomena for substances of lower molecular weight and less structural complexity suggested that exogenous proteins should normally be excluded from the CNS.


Nerve Growth Factor Tight Junction Protein Uptake Hypertonic Solution Exogenous Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Emanuel Levin
    • 1
    • 2
  • Carlos E. Tradatti
    • 1
    • 2
  1. 1.Instituto Nacional de Farmacología y BromatologíaCaserosUSA
  2. 2.Instituto Antártico ArgentinoBuenos AiresArgentina

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