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Pathways of Lipoprotein Metabolism: Integration of Structure, Function and Metabolism

  • S. Eisenberg
  • D. Rachmilewitz
  • R. I. Levy
  • D. W. Bilheimer
  • F. T. Lindgren
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 63)

Abstract

The plasma lipoproteins are complex structures composed of proteins and lipids and involved with the transport of lipids in the circulation. The various lipoproteins are customarily separated into several groups following their flotation properties in salt solutions. Lipoproteins thus obtained differ in size, particle weight, lipid and protein composition, electrophoretic mobility and other physical and chemical properties. Yet, the lipoprotein system resembles more a continuous spectrum of particles of changing composition than families of distinct and discernible character. This is especially true for the lower density lipoproteins — chylomicrons, VLDL and LDL. Clearly, the classification of lipoproteins is somewhat arbitrary and a functional approach towards the lipoproteins is needed.

Keywords

Lipoprotein Lipase Lower Density Lipoprotein Lipoprotein Metabolism VLDL Particle Unesterified Cholesterol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • S. Eisenberg
    • 1
  • D. Rachmilewitz
    • 1
  • R. I. Levy
    • 2
  • D. W. Bilheimer
    • 3
  • F. T. Lindgren
    • 4
  1. 1.Lipid Research Laboratory, Department of Medicine BHadassah University HospitalJerusalemIsrael
  2. 2.Division of Heart and Vaschular DiseasesNational Heart and Lung InstituteBethesdaUSA
  3. 3.Southwestern Medical SchoolUniversity of TexasDallasUSA
  4. 4.Donner LaboratoriesUniversity of CaliforniaBerkeleyUSA

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