Planning the Type II Coronary Primary Prevention Trial of the Lipid Research Clinics (U. S. A.)

  • Daniel Steinberg
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 63)


One of the important potential functions for an organized system of cooperating lipid research clinics is to serve as a framework for large-scale intervention studies, studies beyond the scope of any individual clinic. The Lipid Research Clinics in the United States, sponsored by the National Heart and Lung Institute, are already embarked on such a large-scale study and the experience gained in the planning stages may be helpful to other groups contemplating related studies. My purpose today is to share with you some examples of the problems that were encountered rather than attempt a complete review of that study. This is the report not of an epidemiologist but a physician and it will be more anecdotal than analytical.


Lipid Research Clinic Coronary Heart Disease Death Lung Institute Lower Serum Cholesterol Level Reduce Serum Cholesterol Level 
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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Daniel Steinberg
    • 1
  1. 1.Division of Metabolic Disease, Department of Medicine, San Diego School of MedicineUniversity of CaliforniaCaliforniaUSA

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