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Lipoproteins and Lipid Transport

  • Richard J. Havel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 63)

Abstract

Lipids are transported in blood plasma in association with proteins. Some polar lipids are transported by albumin (free fatty acids, bile acids) or by specific binding proteins (retinol-binding protein). Nonpolar lipids are transported in large complexes containing polar lipids and specific apoproteins (which serve functions beyond that of “packaged”). These complexes comprise the macromolecular particles that we generally think of when we apply the term “lipoproteins” to blood plasma and other extracellular fluids. These lipoproteins and their role in transport of nonpolar lipids are the subject of this short and eclectic review.

Keywords

Polar Lipid Cholesteryl Ester Lipoprotein Lipase Lipid Transport Nonpolar Lipid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations used in this paper

VLDL

LDL and HDL are very low density, low density and high density lipoproteins

LCAT

lecithin-cholesterol acyl transferase

A

apoproteins refer to the two major apoproteins of HDL, B-apoprotein to the major apoprotein of LDL and C-apoproteins to the three proteins of low molecular weight that are shared between VLDL and HDL in humans and rats.

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Richard J. Havel
    • 1
  1. 1.Cardiovascular Research Institute and Department of MedicineUniversity of CaliforniaSan FranciscoUSA

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