Studies on Experimental Atherosclerosis by Immunofluorescence

  • Kenneth W. Walton
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 63)


It has been established by several investigators (e. g., Watts, 1959, 1963; Woolf and Pilkington, 1965; Kao and Wissler, 1965; Walton, 1966; Walton and Williamson, 1968; Walton et al., 1970), using the technique of immunofluorescence, that the principal vehicle transporting lipid into human atherosclerotic lesions, is serum low-density lipoprotein (LDL). The purpose of the present study was to see whether a similar technique could be applied to the arterial lesions of lipid-fed rabbits.


Immunofluorescence Study Specific Fluorescence Arterial Lesion Aortic Lesion Experimental Atherosclerosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gresham, G. A. and Howard, A.N.: Arch. Pathol. 74: 1, 1962.PubMedGoogle Scholar
  2. 2.
    Kao, V. C. Y. and Wissler, R. W.: Exp. Molec. Path. 4: 457, 1965.CrossRefGoogle Scholar
  3. 3.
    Saint-Marie, G.: J. Histochem. Cytochem. 10: 250, 1962.CrossRefGoogle Scholar
  4. 4.
    Walton, K. W.: Arch. Mal Coeur, 59, suppl. 2, p. 41, 1966.Google Scholar
  5. 4a.
    Walton, K. W.: Revue Atheroscler., 8 suppl. 2, p. 41, 1966.Google Scholar
  6. 5.
    Walton, K. W.: Nutr. Metab. 15: 37, 1973a.CrossRefGoogle Scholar
  7. 6.
    Walton, K. W.: J. Path. Ill: 263, 1973.Google Scholar
  8. 7.
    Walton, K. W.: In J. C. Brocklehurst (ed.) Textbook of Geriatric Medicine and Gerontology, pp. 77–112, London, Churchill-Living stone, 1973c.Google Scholar
  9. 8.
    Walton, K. W.: Nutr. Metab. 15: 59, 1973d.PubMedCrossRefGoogle Scholar
  10. 9.
    Walton, K. W. and Dunkerley, D. J.: J. Path., in press.Google Scholar
  11. 10.
    Walton, K. W., Thomas, C. and Dunkerley, D. J.: J. Path. 109: 271, 1973.PubMedCrossRefGoogle Scholar
  12. 11.
    Walton, K. W. and Williamson, N.: J. Atheroscler. Res. 8: 599, 1968.PubMedCrossRefGoogle Scholar
  13. 12.
    Walton, K. W., Williamson, N. and Johnson, A. G.: J. Path. 101: 205, 1970.PubMedCrossRefGoogle Scholar
  14. 13.
    Watts, H. F.: Amer. J. Path. 35: 719, 1959.Google Scholar
  15. 14.
    Watts, H. F.: In R. J. Jones (ed.) Evolution of the atherosclerotic plaque, p. 116, Chicago, Chicago University Press, 1963.Google Scholar
  16. 15.
    Woolf, N. and Pilkington, T. R. E.: J. Path. Bact. 90: 459, 1965.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Kenneth W. Walton
    • 1
  1. 1.Department of Experimental PathologyUniversity of BirminghamEngland

Personalised recommendations