Some Aspects of the Chimpanzee as a Model for Experimental Atherosclerosis

  • M. Vastesaeger
  • H. Peeters
  • V. Blaton
  • C. Petrovas
  • J. Mortelmans
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 63)


The main objective of experimental atherosclerosis is to start in anima vili the atherogenic process in such a way as to be able to study its cause or causes, its development and its effects. However, such an ambitious program is nearly impossible to carry out if one wishes to extrapolate the experimental observations in spontaneous human atherosclerosis. Indeed, the latter is a multifactorial phenomenon in which metabolic elements play without a doubt a major but certainly not the only role.


Cholesterol Ester Familial Hypercholesterolemia Lipoproteinic Profile Atherogenic Diet Experimental Atherosclerosis 


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  1. 1.
    Blaton, V., Vastesaeger, M., Van Damme, D. and Peeters, H. Exp. Mol. Path. 20: 132, 1974.CrossRefGoogle Scholar
  2. 2.
    Clarkson, T. B., Prichard, R. W., Netsky, M. G. and Lofland, H. B. A. M. A. Arch. Path. 68: 143, 1959.PubMedGoogle Scholar
  3. 3.
    Delcourt, R., Ninane, G., Osterrieth, P. and Vastesaeger, M. Acta Cardiol. 19:531, 1964.PubMedGoogle Scholar
  4. 4.
    Goodall, J. Nat. Geographic 124, 1963.Google Scholar
  5. 5.
    Keys, A., Anderson, J. J., Fidanza, F., Keys, M. H., and Swahn, B. Clin. Chem. 1: 34, 1955.PubMedGoogle Scholar
  6. 6.
    Lehner, N. D. M., Clarkson, T. B., Bullock, B. C., Lofland, H. B., St. Clair, R. W. and Prichard, R. W. Medical Primatology, 1970. Proc. 2nd Conference Exp. Med. Surg. Primates, New York, 1969. Karger, Basel, 1971, p. 873.Google Scholar
  7. 7.
    Lofland, H. B. In: Comparative Atherosclerosis, edited by J. C. Roberts and R. Straus. Hoeber, Harper and Row, New York, 1965.Google Scholar
  8. 8.
    Mann, G. V. Circulat. Res. 18: 205, 1966.Google Scholar
  9. 9.
    Mann, G. V. Medical Primatology, 1972. Proc. 3rd Conf. Exp. Med. Surg. Primates, Lyon, 1972.Google Scholar
  10. 10.
    Morris, M. D. and Geer, W. E. In: Atherosclerosis. Edited by R. J. Jones, Springer Verlag, Heidelberg, 1970, p. 192.Google Scholar
  11. 11.
    Paloheimo, J. Ann. Med. Exp. Biol. Fenn. 39 (Supplement 8): 1–88, 1961.PubMedGoogle Scholar
  12. 12.
    Petrovas, C., Vanderveiken, F., Blaton, V., Peeters, H. and Vastesaeger, M., to be published.Google Scholar
  13. 13.
    Prichard, R. W. In: Comparative Atherosclerosis, edited by J. C. Roberts and R. Straus. Hoeber, Harper and Row, New York, 1965.Google Scholar
  14. 14.
    Stehbens, W. E. Proc. Royal Soc. London 185: 357, 1974.CrossRefGoogle Scholar
  15. 15.
    Thomas, C. B., Holljes, H. W. D. and Eisenberg, F. F. Arm. Int. Med. 54: 413, 1961.Google Scholar
  16. 16.
    Vastesaeger, M. and Delcourt, R. Acta Cardiol. Supplement XI: 283, 1966.Google Scholar
  17. 17.
    Vastesaeger, M., Vercruysse, J. and Martin, J. J. Medical Primatology, 1972, Proc. 3rd Conf. Exp. Med. Surg. Primates, Lyon, 1972. Karger, Basel, 1972.Google Scholar
  18. 18.
    Vastesaeger, M., Blaton, V., Declercq, B., Vercruysse, J., Van Damme, D., Peeters, H. and Mortelmans, J. Acta Zool. Path. Antverpiensia 58: 74, 1974.Google Scholar
  19. 19.
    Vastesaeger, M., Vanderveiken, F., Gillot, P. and Petrovas, C., to be published.Google Scholar

Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • M. Vastesaeger
    • 1
  • H. Peeters
    • 2
  • V. Blaton
    • 2
  • C. Petrovas
    • 3
  • J. Mortelmans
    • 4
  1. 1.University of BrusselsBelgium
  2. 2.Simon Stevin Instituut voor Wetenschappelijk onderzoekBruggeBelgium
  3. 3.Centre d’Etude des Maladies des Arteres CoronairesBrusselsBelgium
  4. 4.Royal Zoological SocietyAntwerpenBelgium

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