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Structural and Functional Aspects of the Protein Synthesizing Apparatus in the Rough Endoplasmic Reticulum

  • David D. Sabatini
  • George Ojakian
  • Mauricio A. Lande
  • John Lewis
  • Winnie Mok
  • Milton Adesnik
  • Gert Kreibich
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 241)

Abstract

The successful implementation of a genetic program requires that upon completion of translation polypeptides released from ribosomes are transferred to their final destination in the cell This appears to be a rather formidable process since, in a eukaryotic cell, the fate of a protein can be at least as diverse as the membranous structures within the cell and the subcellular compartments which they separate. For many proteins, these subcellular compartments serve only as the initial destination; transfer to another compartment or export from the cell may be their ultimate fate.

Keywords

Large Subunit Rough Endoplasmic Reticulum Ribosomal Subunit Endoplasmic Reticulum Membrane Microsomal Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • David D. Sabatini
    • 1
  • George Ojakian
    • 1
  • Mauricio A. Lande
    • 1
  • John Lewis
    • 1
  • Winnie Mok
    • 1
  • Milton Adesnik
    • 1
  • Gert Kreibich
    • 1
  1. 1.Department of Cell BiologyNew York University School of MedicineNew YorkUSA

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