Preformed mRNA and the Programming of Early Embryo Development

  • Abraham Marcus
  • Sara Spiegel
  • John D. Brooker
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 241)


Growth and development of an organism can be characterized as the implementation of a series of sequentially operative genetic programs. The process includes first a determination of the particular program, i.e. selectivity at the level of genomic transcription, and then either an immediate proceeding into its application, i.e. translation, or alternatively, holding the program in abeyance awaiting an activation reaction. In two systems, both of which involve early embryonic development, there appears to be substantial evidence that the latter of these two alternatives, namely the activation of a previously transcribed program, does indeed serve as a significant control. The systems are the fertilization of echinoderm and amphibian eggs, and the germination of seed embryos.


Isocitric Lyase Early Embryo Development Seed Embryo Wheat Embryo Template Activity 


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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Abraham Marcus
    • 1
  • Sara Spiegel
    • 1
  • John D. Brooker
    • 1
  1. 1.Fox Chase Center for Cancer and Medical SciencesThe Institute for Cancer ResearchPhiladelphiaUSA

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