The History of Parenteral Alimentation

  • Hans H. Bode
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 46)


Ever since William Harvey announced his theory of circulation in 1615, man has attempted to cure disease by cleansing or enriching the blood with infusion of intravenous remedies. Among the first to investigate this means of therapy was another famous Englishman, Sir Christopher Wren. He performed intravenous infusion in animals and discussed the benefits of blood transfusion, a technique that was undertaken in animals by Richard Lower in 1665 and ten years later by Jean Baptiste Denis who transfused sheep blood into humans. Fortunately, when these early studies met with little success or frequently even with disaster, the initial enthusiasm for human experimentation declined. Gauthier invented a technique for the distillation of water in 1717, and sixteen years later Stephen Hales produced “dropsy” in humans by infusing water intravenously. The study of metabolism was initiated by Lavoisier later in that century, and in 1792 glucose was discovered by Lobowitz.


Parenteral Nutrition Hypertonic Solution Burns Institute Hypodermic Syringe Synthetic Diet 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Abderhalden, E., Frank, F. and Schittenlehn, A. Hoppe-Seylers, Z. Physiol. Chem. 631:215, 1909.CrossRefGoogle Scholar
  2. 2.
    Coats, D.A. Anaesthes. Wiederbel.6:142, 1966.Google Scholar
  3. 3.
    Dudrick, S.Y. In: Intravenous Hyperalimentation, G.S.M. Cowan and W.L. Scheetz, Eds. Philadelphia, Lea and Febiger, p. v, 1972.Google Scholar
  4. 4.
    Farr, L.E. and Mac Fadyen, D.H. Proc. Soc. Exp. Biol.(NY)42: 444, 1939.Google Scholar
  5. 5.
    Garrison, F.H. An Introduction to the History of Medicine. Philadelphia, W.B. Saunders Co., p. 809, 1929.Google Scholar
  6. 6.
    Geyer, R.P., Matthews, L.W. and Stare, F.J. J. Biol. Chem.:180:1037, 1949.Google Scholar

Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • Hans H. Bode
    • 1
  1. 1.Children’s Service, Harvard Medical SchoolMassachusetts General Hospital and Shriners Burns InstituteBostonUSA

Personalised recommendations