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The Molecular Biology of the Steroid Hormones

  • Gordon M. Tomkins
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 44)

Abstract

In man and the other vertebrates, hormones are produced in small quantity in specialized endocrine cells in response to physiological or developmental stimuli, reach their target tissues through the circulation, and induce specific cellular reactions tending either to restore metabolic balance or promote differentiation. Our work has primarily been concerned with the mechanism of glucocorticoid action. Before beginning a discussion of the specific molecular details however, I should like to make some general remarks about the evolution and biology of the hormones, since important clues on fundamental mechanisms in present-day organisms might be found by considering their evolutionary history.

Keywords

Hepatoma Cell Acceptor Site Complex Biological Process Specialized Endocrine Cell Cellular Communication Network 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Gordon M. Tomkins
    • 1
  1. 1.Department of Biochemistry and BiophysicsUniversity of California, San FranciscoSan FranciscoUSA

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