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Initiation of Transcription by RNA Polymerases of E. Coli and Phage T3

  • E. K. F. Bautz
  • W. T. McAllister
  • H. Küpper
  • E. Beck
  • F. A. Bautz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 44)

Abstract

Unlike eukaryotes, bacteria possess only a single species of RNA polymerase which is responsible for the expression of the entire genetic information of the cell. Evidence for a single enzyme comes from the action of the drug rifampicin, which interacts with RNA polymerase and upon addition to a cell culture eliminates the synthesis of ribosomal, transfer and messenger RNA. A single-step mutation of rifampicin resistance restores the ability to synthesize all RNA species in the presence of the drug (1).

Keywords

Phosphodiester Bond Nucleoside Triphosphate Promotor Site Core Enzyme Allosteric Effector 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • E. K. F. Bautz
    • 1
  • W. T. McAllister
    • 1
  • H. Küpper
    • 1
  • E. Beck
    • 1
  • F. A. Bautz
    • 1
  1. 1.Institut für Molekulare Genetik Universität Heidelberg69 HeidelbergWest Germany

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