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Faulty Proteins: Altered Gene Products in Senescent Cells and Organisms

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Control of Gene Expression

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 44))


The process of senescence is characterized by a progressive inability of the individual organism to defend itself against environmental insults. Superficially, the deterioration of the aging organism may appear to be composed of various degenerative processes occurring simultaneously. However, in attempting to formulate the simplest possible explanation for the many alterations observed in senescence, that is, to present a theory of aging, the initial causes of the modifications occurring at the subcellular level, whose effects are then expressed as the gross defects observed in the aging organism, should be considered.

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© 1974 Plenum Press, New York

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Gershon, H., Zeelon, P., Gershon, D. (1974). Faulty Proteins: Altered Gene Products in Senescent Cells and Organisms. In: Kohn, A., Shatkay, A. (eds) Control of Gene Expression. Advances in Experimental Medicine and Biology, vol 44. Springer, Boston, MA.

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  • Print ISBN: 978-1-4684-3248-0

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