Regulation of Developmental Pathways Following Infection of Escherichia Coli by Bacteriophage Lambda

  • Amos B. Oppenheim
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 44)


The temperate bacteriophage lambda can be present in several forms. On infection of the host, it can grow and multiply along the lytic cycle, leading to the production of 100 progeny phages in about 1 h. When conditions for this are unfavorable, alternatively the infected complex may follow the lysogenic pathway (see Fig. 1). Following the establishment of the lysogenic condition, which requires phage repression and integration of phage into the bacterial chromosome, the prophage multiplies passively with the bacterial chromosome. Phage can occasionally be induced spontaneously, or by appropriate treatment which destroys repression, such as UV irradiation or by heating cells harboring prophage and a thermolabile repressor.


Developmental Pathway Bacteriophage Lambda Bacterial Chromosome Lytic Cycle Infected Complex 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Amos B. Oppenheim
    • 1
  1. 1.Department of Microbiological ChemistryThe Hebrew University-Hadassah Medical SchoolJerusalemIsrael

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