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Age Related and Atherosclerotic Changes in Aortic Elastin

  • S. M. Partridge
  • F. W. Keeley
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 43)

Abstract

A point we wish to make is the fact that although there has been a great deal of work on dietary fats and their effects on plasma lipids and the effects of these lipids on the development of fatty plaques in the arterial wall, there has been remarkably little effort put into the attempt to find out what components of the arterial connective tissue are damaged at the site of the fatty or calcified plaques, or which of the normal components of the wall are particularly susceptible to fat deposition or calcification. Other questions to be dealt with are how these components of the wall are normally protected and why the damage is so sharply localized.

Keywords

Surface Active Substance Polar Amino Acid Water Space Concentric Lamina Bovine Aorta 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Brown, H.P. (1953). U.S. Patent 2662874.Google Scholar
  2. Franzblau, C., Sinex, M., Faris, B., and Lampidis, R. (1965). Biochim. Biophys. Res. Commun. 21, 572.Google Scholar
  3. Gosline, J.M. (1973). (Personal communication). Hall, D.A. (1959). Int. Rev. Cytol. 8, 211.Google Scholar
  4. Harkness, M.L.R., Harkness, R.D., and McDonald, D.A. (1957). Proc. Roy. Soc., Ser. B. 146, 541.Google Scholar
  5. Keeley, F.W., and Partridge, S.M. (1973). (In preparation).Google Scholar
  6. Lent, R.W., Smith, B., Salcado, L.L., Faris, B., and Franzblau, C. (1969). Biochemistry 8, 2837.PubMedCrossRefGoogle Scholar
  7. Meyer, R.H. (1950). “Natural and Synthetic High Polymers.” 2nd ed. Interscience Publ., New York.Google Scholar
  8. Molinari-Tosatti, M.P., Galzigna, L., Moret, V., and Gotte, L. (1968). Calcif. Tissue Res. 2, (Suppl.), 88.CrossRefGoogle Scholar
  9. Partridge, S.M. (1966). Fed. Proc. 25, 1023.PubMedGoogle Scholar
  10. Partridge, S.M. (1967a). Biochim. Biophys. Acta 140, 132. Partridge, S.M. (1967b). Nature 213, 1123.Google Scholar
  11. Sandberg, L.B., Weissman, N., and Smith, D.W. (1969). Biochemistry 8, 2940.PubMedCrossRefGoogle Scholar
  12. Smith, D.W., Brown, D.M., and Carnes, W.H. (1972). J. Biol. Chem. 247, 2427.Google Scholar
  13. Smith, D.W., Weissman, N., and Carnes, W.H. (1968). Biochem. Biophys. Res. Commun. 31, 309.Google Scholar
  14. Starcher, B.C., Partridge, S.M., and Elsden, D.F. (1967). Biochemistry 6, 2425.PubMedCrossRefGoogle Scholar
  15. Sykes, B.C., and Partridge, S.M. (1972). Biochem. J. 130, 1171.Google Scholar
  16. Thomas, J., Elsden, D.F., and Partridge, S.M. (1963). Nature 200, 651.PubMedCrossRefGoogle Scholar
  17. Urry, D.W. (1971). Proc. Nat. Acad. Sci. U.S.A. 68, 810.Google Scholar
  18. Weis-Fogh, T., and Amos, W.B. (1972). Nature 236, 301.PubMedCrossRefGoogle Scholar
  19. Weis-Fogh, T., and Anderson, S.O. (1970). Nature 227, 718.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • S. M. Partridge
    • 1
    • 2
  • F. W. Keeley
    • 1
    • 2
  1. 1.Agricultural Research CouncilMeat Research InstituteLangford, BristolUK
  2. 2.Research InstituteThe Hospital for Sick ChildrenToronto 2Canada

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