Acid Glycosaminoglycan, Collagen and Elastin Content of Normal Artery, Fatty Streaks and Plaques

  • Elspeth B. Smith
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 43)


The intimal connective tissue plays a major role in atherosclerosis. It is directly concerned in the proliferative changes leading to stenosis, and appears to be significantly involved in lipid accumulation. The purpose of this paper is to relate the available information on the amounts of acid glycosaminoglycans (GAG), collagen,and elastin in the human intima to the amounts of intact intimai lipoprotein and of bound or precipitated lipid. It is clear that there are major gaps in our knowledge, and that this is an area in which further work is urgently required.


Fatty Streak Internal Elastic Lamina Fibrous Plaque Ulcerate Plaque Connective Tissue Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Elspeth B. Smith
    • 1
  1. 1.Department of Chemical PathologyUniversity of AberdeenForesterhill, AberdeenScotland

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