Enzymic vs Non-Enzymic Factors in the Deterioration of Connective Tissue

  • Frank S. LaBella
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 43)


The term “elastase” has been used to designate enzyme activity that promotes dissolution, “elastolysis”, of native elastic fibers or elastic lamellae and of the constituent elastic protein itself, irrespective of the state of purity of the substrate. Elastic structures consist of a reversibly extensible protein, elastin, embedded in a complex matrix of proteins, glycoproteins and glycosaminoglycans. The associations of elastin with these other substances range from weak electrostatic interactions to stable covalent bonds.


Amino Acid Composition Polar Amino Acid Human Aorta Elastase Activity Soluble Collagen 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Frank S. LaBella
    • 1
  1. 1.Faculty of MedicineUniversity of ManitobaWinnipegCanada

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