Biological Effects of Heavy Metal Pollutants in Water

  • Rolf Hartung
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 40)


I beg your indulgence if I begin my presentation with a brief review of toxicological principles. Toxicology covers the entire range of harmful interactions of chemical substances with the biota. This therefore expands the range from studying very acute effects down to the study of exceedingly subtle changes in behavior and function after long-term exposure for the determination of safety. The studies of functional deficits, carcinogenicity and teratogenicity are well established in toxicological investigations, at least for the safety evaluation of drugs, pesticides, and food additives for man. Studies on subtle behavioral changes and mutagenicity are gaining increasing acceptance. The types of measurements which have been noted most frequently for the study of heavy metals in water are lethality, growth, and reproduction. Behavioral changes and alterations in community structure are not normally investigated, even though they might have sizeable repercussions on the sustained survival of any species.


Heavy Metal Aquatic Organism Methyl Mercury Fathead Minnow Soft Water 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Literature Cited

  1. Anderson, B. G. (1948), Trans. Amer. Fish Soc, 78, 96–113.CrossRefGoogle Scholar
  2. A.P.H.A. (1971), Standard Methods for the Examination of Water and Wastewater, 13th ed., A.P.H.A., Washington, D. C.Google Scholar
  3. Axelsson, B. and Piscator, M. (1966), Arch. Env. Hlth., 12, 360–373.Google Scholar
  4. Ball, I. A. (1967), Water Research, 1, 805–806.CrossRefGoogle Scholar
  5. Bellrose, F. C. (1951), Trans. N. Amer. Wildl. Conf., 16, 125–135.Google Scholar
  6. Bellrose, F. C. (1959), Bull. III. Nat. Hist. Survey, 27(3), 235–288.Google Scholar
  7. Black, J. A., Roberts, R. F., Johnson, D. M., Minicucci, D. C., Mancy, K. H., and Allen, H. E. (1971), Abstracts of Papers, Div. Water, Air & Waste Chem. 162nd Nat. Meeting of the Amer. Chem. Soc, Washington, D. C., Sept. 13–17.Google Scholar
  8. Bork, K., Wanntorp, H., Erne, K., and Hanko, E. (1969), Viltrery, 6(4), 301–379.Google Scholar
  9. Cairns, J., Jr. and Scheier, A. (1968), Progr. Fish Cult., 30(1), 3–8.CrossRefGoogle Scholar
  10. Clarkson, T. W. (1972), Biotransformation of organomercurials in mammals, Environmental Mercury Contamination, R. Härtung and B. D. Dinman, eds., Ann Arbor Science Pub I., pp. 229–238.Google Scholar
  11. Crandall, C. A. and Goodnight, C. J. (1962), Limnol. Oceanogr., 7, 233–239.CrossRefGoogle Scholar
  12. Dinman, B. D. and Hecker, L. H. (1972), The dose-response relationship resulting from exposure to alkyl mercury compounds, Environmental Mercury Contamination, R. Hartung and B. D. Dinman, eds., Ann Arbor Science Publ., pp. 290–301.Google Scholar
  13. Doudoroff, P. and Katz, M. (1953), Sewage Ind. Wastes, 25/7), 802–839.Google Scholar
  14. Dustman, E. H., Stickel, L. F., and Elder, J. B. (1972), Mercury in wild animals, Lake St. Clair, 1970, Envi ronmental Mercury Contamination, R. Hartung and B. D. Dinman, eds., Ann Arbor Science Publ., pp. 46–52.Google Scholar
  15. Hannerz, L. (1968), Fisheries Bd. of Sweden, Inst. for Freshwater Res. Drottningholm, Report No. 48, pp. 120–176.Google Scholar
  16. Henrickson, K., Karppanen, E., and Helminen, M. (1966), Ornis Fennica, 43(2), 38–45.Google Scholar
  17. Hervey, R. K. (1949), Bot. Gas., 11(1), l–11.Google Scholar
  18. Holt, G. (1969), Nord. Vet. Med., 2l, 105–114.Google Scholar
  19. Jernelöv, A. (1972), Factors in the transformation of mercury to methyl mercury, Envi momenta I Mercury Contamination, R. Hartung and D. B. Dinman, eds., Ann Arbor Science Publ., pp. 167–172.Google Scholar
  20. Johnels, A. G. and Westermark, T. (1969), Mercury contamination of the environment in Sweden, Chemical Fallout, M. W. Miller and G. G. Berg, eds., C. C. Thomas Publ., pp. 221–241.Google Scholar
  21. Johnels, A., Westermark, T., Berg, W., Persson, P. I., and Sjostrand, B. (1967), Oikos, 18, 323–333.CrossRefGoogle Scholar
  22. Jordan, J. S. (1952), Univ. of Mich. Ph.D. Thesis, 144 pp.Google Scholar
  23. Jordan, J. S. and Bellrose, F. C. (1951), Biol. Notes No. 26, III. Nat. History Survey, Urbana, III.Google Scholar
  24. Landner, R. (1971), Nature, 230, 452–453.PubMedCrossRefGoogle Scholar
  25. Lloyd, R. (1960), Ann. Appl. Biol., 48, 84–94.CrossRefGoogle Scholar
  26. Mancy, K. H. (1972), Copper toxicity to fishes in natural waters, Progress Report FWQA 14–12-591.Google Scholar
  27. McKee and Wolf, H. W. (1963), Water Control Criteria, Calif. State Water Quality Control Board, Sacramento, Publ. 3A, 548 pp.Google Scholar
  28. Miettinen, V., Blankenstein, E., Rissanen, K., Tillander, M., Miettinen, J. K., and Valtonen, M. (1970), FAO Tech. Conf. on Marine Pol lut., Rome, Italy, Dec. 9–18.Google Scholar
  29. Mount, D. I. (1966), Air Wat. Pollut. Ind. J., 10, 49–56.Google Scholar
  30. Mount, D. I. and Stephan, C. E. (1969), J. Fish. Res. Bd. Can., 29, 2449–2457.CrossRefGoogle Scholar
  31. National Institute of Public Health, Sweden (1971), Methylmercury in fish, Nordish Hygienish Tidshrift, Suppl. 4, 364 pp.Google Scholar
  32. Pickering, Q. H. and Henderson, C. (1965), Proc. 19th Ind. WasteGoogle Scholar
  33. Conf. Purdue Univ.; (1966), Air Water Pol lut., 10(6/7), 453–463.Google Scholar
  34. Schroeder, H. A. and Buckman, J. (1967), Arch. Env. Hlth., 14, 693–697.Google Scholar
  35. Skidmore, J. (1964), Quart. Rev. Biol., 39(3), 227–248.PubMedCrossRefGoogle Scholar
  36. Sprague, J. B. (1964), J. Fish. Res. Bd. Can., 21, 17–26.CrossRefGoogle Scholar
  37. Stiff, M. J. (1971), Water Research, 5, 171–176.CrossRefGoogle Scholar
  38. Takeuchi, T. (1972), Biological reactions and pathological changes in human beings and animals caused by organic mercury contamination, Environmental Mercury Contamination, R. Hartung and B. D. Dinman, eds., Ann Arbor Science Publ., pp. 247–289.Google Scholar
  39. Tsuchiya, K. (1969), Keio J. Med., 18, 181–211.PubMedCrossRefGoogle Scholar
  40. Velsen, F. J. P. and Alderdice, D. F. (1967), J. Fish Res. Bd. Can., 24, 1173–1175.CrossRefGoogle Scholar
  41. Weir, P. A. and Hine, C. H. (1970), Arch. Env. Hlth., 20, 45–51.Google Scholar
  42. Wood, J. M., Kennedy, S. F. and Rosen, C. G. (1968), Nature, 220, 173–174.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • Rolf Hartung
    • 1
  1. 1.Department of Environmental and Industrial HealthThe University of MichiganAnn ArborUSA

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