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Addiction to Barbiturates and Ethanol: Possible Biochemical Mechanisms

  • Boris Tabakoff
  • Frieda Ungar
  • S. G. A. Alivisatos
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 35)

Abstract

The possible interaction between ethanol and the metabolism of biogenic amines in brain tissue has long been an area of concerted research. However, only recently have viable theories emerged which may lead to an understanding of the particular biochemical interaction that might be responsible for the development of a state of addiction to ethanol. Such theories have been nurtured by a recognition of a common pathway of catabolism for the deaminated derivatives of the biogenic amines and acetaldehyde, the initial metabolite of ethanol.

Keywords

Brain Tissue Biogenic Amine Aldehyde Dehydrogenase Condensation Product Isoquinoline Alkaloid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • Boris Tabakoff
    • 1
  • Frieda Ungar
    • 1
  • S. G. A. Alivisatos
    • 1
  1. 1.Department of BiochemistryThe Chicago Medical SchoolChicagoUSA

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