Hypothalamic-Pituitary-Adrenal Function in Chronic Alcoholics

  • Julius Merry
  • Vincent Marks
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 35)


It has long been held that alcoholics are resistant to certain hypnotics — including barbiturates — but there is experimental evidence to support this in only a few cases and then only for some of the many barbiturates tested (French, 1971). It is well established, however, that the hypnotic effects of alcohol and barbiturates are additive. These two facts suggest that alcohol and barbiturates may act on the same, or similar, cerebral “receptor” sites.


Chronic Alcoholic Alcohol Withdrawal Chronic Alcoholism Blood Alcohol Level Adrenocortical Function 
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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • Julius Merry
    • 1
  • Vincent Marks
    • 2
  1. 1.West Park HospitalEpsom, SurreyUK
  2. 2.Department of BiochemistryUniversity of SurreyUK

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