Abstract
It has long been held that alcoholics are resistant to certain hypnotics — including barbiturates — but there is experimental evidence to support this in only a few cases and then only for some of the many barbiturates tested (French, 1971). It is well established, however, that the hypnotic effects of alcohol and barbiturates are additive. These two facts suggest that alcohol and barbiturates may act on the same, or similar, cerebral “receptor” sites.
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Merry, J., Marks, V. (1973). Hypothalamic-Pituitary-Adrenal Function in Chronic Alcoholics. In: Gross, M.M. (eds) Alcohol Intoxication and Withdrawal I. Advances in Experimental Medicine and Biology, vol 35. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3234-3_10
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DOI: https://doi.org/10.1007/978-1-4684-3234-3_10
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