Platelet Factor 3 — Properties and Clinical Significance

  • G. de Gaetano
  • J. Vermylen
  • M. Verstraete
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


Bounameaux (2) suggested that the periphery of the platelet has a “plasmatic atmosphere” containing many plasma substances, all identified on the basis of their activity. Several so-called “platelet factors” have since then been described (Table I) (20); for most of them, however, it is not possible to state at present if they are specific constituents of platelets or if they come from the plasma; in contrast, some other factors such as phospholipid-like activity (platelet factor-3, PF-3) and antiheparin activity (platelet factor-4) seem to be specific platelet constituents.


Platelet Aggregation Human Platelet Platelet Factor Platelet Membrane Ethanolamine Phosphatidyl 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • G. de Gaetano
    • 1
  • J. Vermylen
    • 1
  • M. Verstraete
    • 1
  1. 1.Laboratory of Blood CoagulationUniversity of LeuvenBelgium

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