Abstract
Bounameaux (2) suggested that the periphery of the platelet has a “plasmatic atmosphere” containing many plasma substances, all identified on the basis of their activity. Several so-called “platelet factors” have since then been described (Table I) (20); for most of them, however, it is not possible to state at present if they are specific constituents of platelets or if they come from the plasma; in contrast, some other factors such as phospholipid-like activity (platelet factor-3, PF-3) and antiheparin activity (platelet factor-4) seem to be specific platelet constituents.
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Supported in part by grant n. 1216 of the Fonds voor Wetenschapelijk Geneeskundig Onderzoek, Belgium.
On leave of absence from the Laboratory of Blood Coagulation (Prof. B. Bizzi), Department of Internal Medicine (Prof. R. Breda), Università Cattolica, Roma, Italy. Fellow of the Ministero della Pubblica Istruzione of Italy.
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de Gaetano, G., Vermylen, J., Verstraete, M. (1972). Platelet Factor 3 — Properties and Clinical Significance. In: Mannucci, P.M., Gorini, S. (eds) Platelet Function and Thrombosis. Advances in Experimental Medicine and Biology, vol 34. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-3231-2_9
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DOI: https://doi.org/10.1007/978-1-4684-3231-2_9
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