Platelet Function Tests and Thrombosis

  • J. R. O’Brien
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


In this review it is proposed first to consider laboratory-tests in general. What are they for? How are they to be judged? The criteria for the diagnosis of thrombosis will be considered and then the functions thought to be involved. Finally some tests preferred by the author will be briefly reviewed against this back-ground information.


Deep Vein Thrombosis Platelet Rich Plasma Bleeding Time Platelet Adhesion Release Mechanism 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Evans D. S., Brit. J. Surg., 57, 726, 1970.PubMedCrossRefGoogle Scholar
  2. 2.
    Flanc C., Kakkar V. V., Clarke M. B., The detection of venous thrombosis of the legs using 125i-labelled fibrinogen. Brit. J. Surg., 55, 742, 1968.Google Scholar
  3. 3.
    Fletcher A. P., Alkjaersig N., O’brien J. R., Tulevski V. G., Trans. Ass. Amer. Physicians, 83, 159, 1970.Google Scholar
  4. 4.
    Kakkar V. V., Field E. S., Nicholases A. N., Flute P. T., Wessler S., Yin E. T., Low doses of heparin in prevention of deep vein thrombosis. Lancet, 2, 669, 1971.PubMedCrossRefGoogle Scholar
  5. 5.
    Haslam R. S., Taylor A., Platelet aggregation Ed. J. Caen, p. 85, 1971.Google Scholar
  6. 6.
    Lambie J. M., Mahaffy R. G., Barber D. C., Karmody A. M., Matheson N. A., Diagnostic accuracy in venous thrombosis. Brit. Med. J., 2, 142, 1970.PubMedCrossRefGoogle Scholar
  7. 7.
    Mielke C. H., Kaneshiro M. M., Maker I. A., Weiner J. M., Rapaport S., The standardized normal Ivy bleeding time and its prolongation by aspirin. Blood, 34, 204, 1970.Google Scholar
  8. 8.
    Negus D., Pinto D. J., Le Quesne L. P., Brown N., Chapman M., 125l-labelled fibrinogen in the diagnosis of deep vein thrombosis and its correlation with phlebography. Brit. J. Surg., 55, 835, 1968.Google Scholar
  9. 9.
    O’brien J. R., Tolevski V., Etherington M., Platelet function tests in pre-and post-operative patients with and without thrombosis. Symposium on “The role of platelets in haemostasis and thrombosis”-Prague. Abstract, p. 46, 1971.Google Scholar
  10. 10.
    O’brien J. R., Tolevski V., Etheringtot M., Two in vivo studies comparing high and low aspirin dosage. Lancet, 1, 379, 1971.Google Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • J. R. O’Brien
    • 1
  1. 1.Portsmouth and Isle of Wight Area Pathology ServiceUK

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