Skip to main content

Mechanisms of Hypothermic Protection Against Anoxia

  • Chapter
Neurohumoral and Metabolic Aspects of Injury

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 33))

Abstract

About 10 p.m. one night some years ago, a junior in a southern medical school was directed to place a just-delivered stillborn infant in the refrigerated storage pending the arrival of the mortician on the following morning. Twelve hr later, when he pulled out the tray and unwrapped the child he was confronted by a cold but pink, very-jnuch-alive infant. The infant was placed immediately in a warm incubator; almost as quickly developed respiratory problems, and within 2 hr was dead (Stallings, personal communication). Similar types of experiences can be recalled by almost any obstetrician who has had wide experience. Are these merely clinical observations for which no explanations can be offered or do they constitute evidence that there may be a neglected approach to the problem of resuscitation of the asphyxiated neonate?

Deceased June 11, 1971

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aufderheide, W. & MLller, J.A., Jr. (1972) Unpublished results.

    Google Scholar 

  • Auld, P.A., Nelson, N.M., Nicopoulos, D. A., Helwig, F. & Smith, C.A. (1962) New Engl., J. Med. 267:1340.

    Article  Google Scholar 

  • Carmichael, S.W. (1971) Dissertation, Tulane Library.

    Google Scholar 

  • Carmichael, S.W. (1971) Submitted to Anat. Rec.

    Google Scholar 

  • Cedercreutz, C. (1971) Personal communication quoted by Westin, B. (1971) Amer. J. Obstet, and Gynecol. 110:1136.

    Google Scholar 

  • Cordey, R. (1961) Bull. Fed. Soc. Gynecol. Obstet Langue Franc. 13:507.

    Google Scholar 

  • Cordey, R. (1964) Obstet. & Gynecol. 24:760.

    Google Scholar 

  • Cordey, R. & Chausse, J.M. (1967) Gynaecol. 163:124.

    Google Scholar 

  • Cordey, R. & Chiolero Reanimation du nouveau-né par hypothermie : données acido-basiques et evolution de 33 enfants à long terme. Manuscript 1972

    Google Scholar 

  • Crow, C.A. (1969) Dissertation, Tulane Library.

    Google Scholar 

  • Dawkins, M.J.R. & Hull, D. (1965) Scientif. Amer. 213:62.

    Article  Google Scholar 

  • Drage, J.S. , Kennedy, C. & Schwartz, B.K. (1964) Obstet. Gynecol. 24:222.

    Google Scholar 

  • Drage, J.S. & Berendes, H. (1966) Pediat. Clin. N.Am. 13:635.

    Google Scholar 

  • Dunn, J.M. & Miller, J.A., Jr. (1969) Aner. J. Obstet. Gynecol. 104:58.

    Google Scholar 

  • Ehrstrom, J., Hirvansalo, M., Donner, M. & Hietalahti, J. (1969) Ann. Clin. Res. 1:40.

    Google Scholar 

  • Krokfors, E., Pitkänen, H., Hirvensalo, Mo & Rhen, K. (1961) Evipanos Suomen Laäkaril 17:937.

    Google Scholar 

  • Miller, J.A., Jr. (1949) Science 110:113.

    Article  Google Scholar 

  • Miller, J.A., Jr. (1965) Bull. Tulane Univ. Med. Faculty 24:193.

    Google Scholar 

  • Miller, J.A., Jr. (1971) Mer. J. obstet. Gynecolo 110:1123.

    Google Scholar 

  • Miller, J.A. & Miller, F.S. (1954) Surgery 36:916.

    Google Scholar 

  • Miller, J.A., Jr. & Miller F.S. (1962) Amer. J. Obstet. Gynecol. 48:44.

    Google Scholar 

  • Rink, R. & Miller, J.A., Jr. (1967) Cryobiol. 4:24.

    Article  Google Scholar 

  • Villee, C.A. (1967) In “Brain Damage in the Fetus and Newborn from Hypoxia or Asphyxia”. Eds. L.S. James & R.E. Myers. Ross Labo Pub. 1967 p. 47.

    Google Scholar 

  • Westin, B. (1971) Amer. J. Obstet. Gynecol. 110:1134.

    Google Scholar 

  • Westin, B., Nyberg, R, Miller, J.A., Jr. & Wedenberg, E. (1962) Acta. Paediat. Suppl. 139:1.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1973 Plenum Press, New York

About this chapter

Cite this chapter

Miller, J.A., Miller, F.S. (1973). Mechanisms of Hypothermic Protection Against Anoxia. In: Kovách, A.G.B., Stoner, H.B., Spitzer, J.J. (eds) Neurohumoral and Metabolic Aspects of Injury. Advances in Experimental Medicine and Biology, vol 33. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3228-2_58

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-3228-2_58

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3230-5

  • Online ISBN: 978-1-4684-3228-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics