Adipose Tissue and Hemorrhagic Shock

  • S. Rosell
  • P. Sándor
  • A. G. B. Kovách
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 33)


The average man has around 15 kg of adipose tissue and as much as 90% of this may be triglycerides. As a consequence, adipose tissue may yield close to the theoretical 9.4 cal/g of pure lipid. The adipose tissue is then by far the largest energy source of the body. It is therefore obvious that it must be of great interest to find out how the adipose tissue reacts during different forms of trauma. There have been a limited number of studies on lipid metabolism, including changes in the plasma FFA level, during trauma. These studies have indicated that there is an increased mobilization of FFA from adipose tissue (Wadström, 1959, Stoner, 1962). Therefore the question has been raised whether high plasma FFA levels produced by elevated mobilization from adipose tissue may be harmful to the individual. It has been argued that heart failure may partly be due to oxidation of fat, since this requires more oxygen than carbohydrate oxidation. Furthermore, high plasma levels of FFA may be the cause of lung embolism.


Adipose Tissue Sympathetic Nerve Hemorrhagic Shock Subcutaneous Adipose Tissue Shed Blood 
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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • S. Rosell
    • 1
    • 2
  • P. Sándor
    • 1
    • 2
  • A. G. B. Kovách
    • 1
    • 2
  1. 1.Dept. of PharmacologyKarolinska InstituteStockholmSweden
  2. 2.Semmelweis Medical UniversityStockholm, BudapestHungary

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