Concepts of Louse-Borne Typhus Control in Developing Countries: The Use of the Living Attenuated E Strain Typhus Vaccine in Epidemic and Endemic Situations

  • Charles L. WissemanJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 31)


Louse-borne or epidemic typhus fever is without doubt one of the great epidemic diseases of mankind whose ebb and flow through the centuries has been important in the molding of human destiny (1). Much of our knowledge about typhus fever has come from experience in the unique setting of the temperate north of Europe (1–16) where its relative importance has declined as living conditions have improved over many years. Indeed, in recent times the epidemic potential of typhus in Europe has been realized primarily in the wake of the catastrophic disruptions caused by wars. Our attitude about relative importance, epidemiology, approaches to control and level of research support has been influenced strongly by the trends in modern, advanced Europe.


Strain Vaccine Late Reaction Localize Outbreak Body Louse Endemic Situation 


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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Charles L. WissemanJr.
    • 1
  1. 1.Department of MicrobiologyUniversity of Maryland School of MedicineBaltimoreUSA

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