The Origin of Pandemic Strains of Influenza. Evidence from Studies of the Structure of the Hemagglutinin Subunits

  • W. G. Laver
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 31)


Influenza continues to be one of the major epidemic diseases of man. Pandemics of influenza A occur at irregular intervals, with intervening outbreaks of reduced severity. Between pandemics the virus slowly changes, undergoing gradual alterations in its surface antigens (immunological, or antigenic drift); but the major epidemics are caused by new virus strains having surface antigens unrelated to those of viruses currently circulating.


Influenza Virus Heavy Chain Tryptic Peptide Avian Influenza Virus Human Influenza Virus 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • W. G. Laver
    • 1
  1. 1.Department of Microbiology, The John Curtin School of Medical ResearchAustralian National UniversityCanberraAustralia

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