Functional Aspects of the Three-Dimensional Structure of the Active Site of Carbonic Anhydrase

  • Ivar Waara
  • Seved Lövgren
  • Anders Liljas
  • K. K. Kannan
  • Per-Christer Bergstén
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


Carbonic anhydrase, which is found in large quantities in red cells is an extremely powerful catalyst of the hydration of carbon dioxide (Khalifah, 1971). The dehydration of bicarbonate is also catalysed at an appreciable rate (Christiansen and Magid, 1970). The enzyme is able to hydrate certain aldehydes (Pocker and Meany, 1965) and hydrolyse a number of esters (Thorslund and Lindskog, 1967).


Carbonic Anhydrase Active Site Cavity Nuclear Magnetic Relaxation Polar Side Chain Human Carbonic Anhydrase 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Ivar Waara
    • 1
  • Seved Lövgren
    • 1
  • Anders Liljas
    • 1
  • K. K. Kannan
  • Per-Christer Bergstén
    • 1
  1. 1.The Wallenberg LaboratoryUniversity of UppsalaUppsalaSweden

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