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Study of Carbohydrate Metabolism in the Newborn Rat as a Tool for Evaluating Effects of Drugs Administered during Pregnancy

  • R. De Meyer
  • G. Verellen
  • P. Gerard
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 27)

Abstract

The effects of drugs on fetal development are usually investigated in early pregnancy, during the period of morphogenesis. However, morphogenesis is not the only mode of differentiation. Aside from building new organs, the fetus must also organize new metabolic functions, and for this purpose, new enzymes have to be induced. These aspects of development may be considered as a metabolic differentiation and one may speculate about the effects of drugs on the development of these metabolic functions. An impairment of metabolic differentiation may be considered as a particular aspect of teratogenesis.

Keywords

Lactic Acid Carbohydrate Metabolism Liver Glycogen Glycogen Level Carbohydrate Store 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • R. De Meyer
    • 1
  • G. Verellen
    • 1
  • P. Gerard
    • 1
  1. 1.Department of PediatricsUniversite Catholique de LouvainLouvainBelgium

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