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Observations on Effects of Analgetic Drugs on Mother and Fetus: Comparison Between Systemic and Local Drug Application during Labor

  • H. Zakut
  • S. Mashiach
  • J. Blankstein
  • D. M. Serr
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 27)

Abstract

When determining the efficiency of a drug, one must consider its ability to give the desired effect, the side effects and the dangers inherent in its administration. These criteria must be evaluated when examining the various analgetics used during labor. In this case, however, we must not forget that we are dealing with two patients — the mother and the fetus. Thus, evaluation of all drugs given during labor must include the following considerations:
  1. 1.

    the influence of the drug on the mother;

     
  2. 2.

    the influence on the course of labor;

     
  3. 3.

    the influence on the fetus and/or the neonate.

     

Keywords

Apgar Score Fetal Heart Rate Uterine Contraction Butyl Bromide Severe Bradycardia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    MOYA, F. THORNDIKE, V. Am. J. Obst. Gynec. 84:1778, 1962.Google Scholar
  2. 2.
    JAFFE, S.J. Ann. Rev. Med. 17: 213, 1966.CrossRefGoogle Scholar
  3. 3.
    FRIEDMAN, E.A. Labour. Meredith Publishing Company, New York, 1967.Google Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • H. Zakut
    • 1
  • S. Mashiach
    • 1
  • J. Blankstein
    • 1
  • D. M. Serr
    • 1
  1. 1.Department of Obstetrics and GynecologyThe Chaim Sheba Medical CenterTel-HashomerIsrael

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