Maternal-Fetal Transport of Iron and Iodine in Human Subjects

  • N. C. Dyer
  • A. B. Brill
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 27)


Information on the absorption, distribution and metabolism of normal body constituents as well as drugs, and toxic materials in man is difficult to obtain. The development of tracer techniques has made it possible to label various components and to follow the distribution of the labelled material. In many circumstances, it is possible to use small amounts of radioactive isotopes as labels, and with this technique accurate results can be obtained with simplicity. In some circumstances, especially in normal pregnant subjects or in normal newborn infants, it is not possible to justify the use of radioactive tracers. In these situations, the same kind of information can often be obtained with stable tracers. This paper will summarize data we have obtained on maternal-fetal transport of the radioactive tracers 131I and 59Fe in women receiving therapeutic abortions and of the stable tracer 58Fe in normal pregnancies.


Fetal Liver Percentage Uptake Absorb Radiation Dose Therapeutic Abortion Fetal Organ 
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  1. 1.
    MEDICAL INTERNAL RADIATION DOSE COMMITTEE, Society of Nuclear Medicine, Inc. J. Nuc. Med. (Suppl.) 9:2, 1968.Google Scholar
  2. 2.
    STERLING, K., LASHOF, J.C. & MAN, E.B. J. Clin. Invest. 33: 1031, 1964.CrossRefGoogle Scholar
  3. 3.
    RALL, J.E., ROBBINS, J. & LEWALLEN, C.G. The Thyroid, in Pincus, G., Thiman, K.V. & Astwod, E.B., The Hormones, Vol. IV, Chap. 3, Academic Press, Inc., New York (1964).Google Scholar
  4. 4.
    POTTER, E.L. Pathology of the Fetus, Chap. 2, Year Book Medical Publishers, Inc., Chicago (1961).Google Scholar
  5. 5.
    DAWES, G.W. Fetal and Neonatal Physiology, Year Book Medical Publishers, Inc., Chicago (1968).Google Scholar
  6. 6.
    DAVIES, J. Human Development Anatomy, The Ronald Press Company, New York (1963).Google Scholar
  7. 7.
    EVANS, T.C., KRETZSCHMAR, R.M., ET AL. J. Nuc. Med. 8: 157, 1967.Google Scholar
  8. 8.
    LAMPE, L., KERTESZ, L. & DZUONYAR, J. Zentralbl. Gynaek. 86: 905, 1964.Google Scholar
  9. 9.
    LAMPE, L., KERTESZ, L. & DZUONYAR, J. Orv. Hetiz. 105: 981, 1964.Google Scholar
  10. 10.
    DUBOIS, E.F., Basal Metabolism in Health and Disease, Chap. 7, Lea F Febiger, Philadelphia (1936).Google Scholar
  11. 11.
    HAHN, P.H., CAROTHERS, E.L., DARBY, W.J., ET AL. Am. J. Obst. and Gynec. 61: 477, 1951.Google Scholar
  12. 12.
    USHER, R. & LIND, J. Acta Paediat. Scand. 54: 419, 1965.PubMedCrossRefGoogle Scholar
  13. 13.
    BRATTEBY, L.E. Acta Paediat. Scand. 57: 132, 1968.PubMedCrossRefGoogle Scholar
  14. 14.
    MOLLISON, P.L., VEAL, N. & CUTBUSH, M. Arch. Dis. Child 25: 242, 1950.PubMedCrossRefGoogle Scholar
  15. 15.
    DYER, N.C., BRILL, A.B., Et al. “Blood Volume and Hemorrhage Timing in Newborn Infants with Respiratory Distress Using the Stable Tracer, 50Cr”, Proceedings of National Topical Meeting of the American Nuclear Society, Neutron Sources and Applications, Augusta, Ga., April 19–21, 1971 (Unpublished data).Google Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • N. C. Dyer
    • 1
  • A. B. Brill
    • 1
  1. 1.Division of Nuclear Medicine and Biophysics School of MedicineVanderbilt UniversityNashvilleUSA

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