Development of the Chick Embryo Limb Buds after Treatment with Nitrogen Mustard, X-Ray Irradiation, or in Vitro Culture
Salzgeber (1,2) studied the teratogenic effect of nitrogen mustard administered to the chick embryo. In more recent work (3) we have observed the development of limb buds after dissection from the chick embryo, immersion in a nitrogen mustard solution and grafting onto a host embryo. Under these experimental conditions, we have obtained the same type of abnormalities as were found on injection of the substance in ovo.
KeywordsChick Embryo Experimental Series Nitrogen Mustard Vitro Culture Tyrode Solution
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