Development of the Chick Embryo Limb Buds after Treatment with Nitrogen Mustard, X-Ray Irradiation, or in Vitro Culture

  • M. Gumpel-Pinot
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 27)


Salzgeber (1,2) studied the teratogenic effect of nitrogen mustard administered to the chick embryo. In more recent work (3) we have observed the development of limb buds after dissection from the chick embryo, immersion in a nitrogen mustard solution and grafting onto a host embryo. Under these experimental conditions, we have obtained the same type of abnormalities as were found on injection of the substance in ovo.


Chick Embryo Experimental Series Nitrogen Mustard Vitro Culture Tyrode Solution 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • M. Gumpel-Pinot
    • 1
  1. 1.Institut d’Embryologie et de Tératologie ExpérimentalesC.N.R.S. et du College de FranceNogent s/MarneFrance

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