The Teratogenic Effect of Cosmetic Constituents on the Chick Embryo
Cosmetic products have a more extended usage than drugs, especially if we consider their wide and habitual usage by healthy people, particularly women. The scent is the particular constituent in these preparations which make their reputation and thus their success on the market; the characteristic bouquet of perfumes, creams, soaps, shampoos, sprays, etc., is obtained by adding different mixtures of essential oils which bear the name of the plants and flowers (1) from which they are extracted in small quantities (rose, citronella, lemon, bergamot oils). Currently, they are produced industrially at high purity; these industrial products are called by their original name, to which the suffix of alcoholic or aldehyde derivate is added (citral = lemon oil, citronellal = citronella oil, etc.).
KeywordsChick Embryo Teratogenic Effect Cosmetic Product Craniofacial Region Limb Malformation
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- 1.The Merck Index. 8th ed., Merck and Co. Inc. Rahway, N.J. (1968).Google Scholar
- 2.Food additives. Substances that are gnerally recognized as safe. Federal Register, 26:3931 (May 9, 1961 ).Google Scholar
- 3.BOYD, E.M. and SHEPPARD, E.P. Arch. Inter. Pharmacodyn. Ther. 188: 5, 1970.Google Scholar
- 4.FEIZER, L.F. and FEIZER, M. Organic chemistry, pp. 937–938, 3rd ed., Reinhold Publish. Corp., N.Y. (1956).Google Scholar
- 5.MOSS, G.P. J. Soc. Cosmet. Chem. 22: 231, 1971.Google Scholar
- 6.ZIBISKER, D.E. Zhur. Microbiol. Epidemiol. i Immunobiol. 31: 15, 1960.Google Scholar
- 7.MSSE, J.R. and LUKAS, G. Arzneimittel Forsch. 7: 687, 1957.Google Scholar
- 9.LEACH, E.H. and LLOYD, J.P.F. Trans. Ophthal. Soc. Un. Kingdom 76: 453, 1956.Google Scholar
- 11.ABRAMOVICI, A. The teratogenic effect of citral on chick embryo. (Unpublished data.)Google Scholar
- 12.MARZULLI, F.N. and MAIBACH, H.J. J. Soc. Cosmet. Chem. 21: 695, 1970.Google Scholar
- 13.WOLFF, ET. Arch. Anat. Hist. Embryol. 22: 1, 1936.Google Scholar