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The Isolation and Characterization of Synaptosomal Plasma Membranes

  • I. G. Morgan
  • M. Reith
  • U. Marinari
  • W. C. Breckenridge
  • G. Gombos
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 25)

Abstract

The importance of methods for the isolation of fractions enriched in neuronal material, synaptosomal fractions (1, 2), synaptic vesicles (3, 5) and synaptosomal plasma membranes (3, 4, 6) can be seen from the large amount of work which has been published on their properties (for review, see 7–10). Unfortunately, despite the proliferation of papers in this field, these fractions have never been thoroughly characterized enzymatically and chemically. We therefore decided to attempt to isolate one of these fractions, the synaptosomal plasma membrane, in a form suitable for further study of its composition.

Keywords

Plasma Membrane Fraction Glycosyl Transferase Synaptosomal Fraction Neuronal Plasma Membrane Plasma Membrane Marker 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • I. G. Morgan
    • 1
    • 2
  • M. Reith
    • 1
  • U. Marinari
    • 1
  • W. C. Breckenridge
    • 1
    • 3
  • G. Gombos
    • 1
    • 4
  1. 1.Faculté de MédecineCentre de Neurochimie du CNRS and Institut de Chimie Biologique67 — StrasbourgFrance
  2. 2.Boursier étranger de l’Institut National de la Santé et de la Recherche MédicaleFrance
  3. 3.Medical Research Council of CanadaCanada
  4. 4.Centre National de la Recherche ScientifiqueFrance

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