Some Problems of Chromosomal Aberration Studies in Meristems

  • John R. K. Savage
  • Morton W. Miller
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 18)


Both dormant and active root meristems are frequently used in the study of radiation cytology as if they were homogeneous cell systems. This assumption is very far from the truth, for heterogeneity is present with regard to cell type, cell stage, cycle and phase times, and the metabolic status of the cells. Moreover, the dormant root is “dormant” when irradiated but “active” when fixed for observation, and the mobilization process introduces additional complications not normally present in roots that have been growing for some time.


Fixation Time Mitotic Index Root Meristem Sensitive Region Tritiated Thymidine 
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  1. 1.
    Clowes, F.A.L. (1961) Duration of the mitotic cycle in a meristem. J. exp. Bot. 12: 283–293.CrossRefGoogle Scholar
  2. 2.
    Evans, H.J. (1962) Chromosome aberrations induced by ionizing radiation. Int. Rev, Cytol. 13: 221–321.CrossRefGoogle Scholar
  3. 3.
    Lea, D.E. (1947) “Actions of radiations on living cells.” (Cambridge university Press).Google Scholar
  4. 4.
    Miller, M. J. and Colaiace, J. D. (1970) Radiation dose fractionation, mitotic index, and multiple fixation studies on chromosome aberrations in Vicia faba. Mutation Res. 10: 449-462.Google Scholar
  5. 5.
    Neary, G.J., and Evans, H.J. (1958) Mitotic delay induced by gamma radiation with and without oxygen in an asynchronous cell population. (Abstr.). Radiat. Res. 9: 159.Google Scholar
  6. 6.
    Savage, J.R.K. (1970) Sites of radiation induced chromosome exchanges. Current topics in Radiation Research 6: 129–194.Google Scholar
  7. 7.
    Savage, J.R.K., and Wigglesworth, D.J. (1970) The nonuniform radiosensitivity of the dormant root meristem of barley seed revealed by chromosome aberrations in cells at metaphase of the first division cycle. Radiat. Bot. 10: 377–390.CrossRefGoogle Scholar
  8. 8.
    Scott, D. and Evans, H.J. (1967) X-ray-induced chromosomal aberrations in Vicia faba: changes in response during the cell cycle. Mutation Res. 4: 579–599.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • John R. K. Savage
    • 1
    • 2
  • Morton W. Miller
    • 1
    • 2
  1. 1.M.R.C. Radiobiology UnitHarwell, Didcot, BerksUK
  2. 2.Dept. of Radiation BiologyThe University of Rochester RochesterNew YorkUSA

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