Cell Division, Development, and Radiation Injury

  • Alan H. Haber
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 18)


This paper deals with two interrelated ideas: (a) the relation of cell division to radiation injury and death, and (b) the consequent usefulness of certain irradiated systems for studying the role of cell division in development.


Cell Division Thymidine Kinase Radiation Injury Relative Biological Effectiveness Chromosome Breakage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Foard, D. E. (1971) The initial protrusion of a leaf primordium can form without concurrent periclinal cell divisions. Can. J. Bot. (in press).Google Scholar
  2. 2.
    Foard, D. E. and Haber, A. H. (1970) Physiologically normal senescence in seedlings grown without cell division after massive gamma-irradiation of seeds. Radiat. Res. 42: 372–380.PubMedCrossRefGoogle Scholar
  3. 3.
    Haber, A. H. (1968) Ionizing radiations as research tools. Ann. Rev. Plant Physiol. 19: 463–489.CrossRefGoogle Scholar
  4. 4.
    Haber, A. H. (1971) Chloroplast senescence in nongrowing tissue in darkness: effects of temperature and age. Exp. Gerontol. 6: 179–185.PubMedCrossRefGoogle Scholar
  5. 5.
    Haber, A. H. and Foard, D. E. (1964) Further studies of gamma-irradiated wheat and their relevance to use of mitotic inhibition for developmental studies. Amer. J. Bot. 51: 151–159.CrossRefGoogle Scholar
  6. 6.
    Haber, A. H., Foard, D. E. and Perdue, S. W. (1969) Actions of gibberellic and abscisic acids on lettuce seed germination without actions on nuclear DNA synthesis. Plant Physiol. 44: 463–467.PubMedCrossRefGoogle Scholar
  7. 7.
    Haber, A. H., Foard, D. E. and Triplett, L. L. (1969) Seedling irradiation of ‘gamma-plantlets’: demonstration and explanation of a leaf growth stimulation. Radiat. Bot. 9: 473–479.CrossRefGoogle Scholar
  8. 8.
    Haber, A. H. and Luippold, H. J. (1959) Dormancy resulting from gamma-irradiation of lettuce seed. Int. J. Radiat. Biol. 1: 317–327.CrossRefGoogle Scholar
  9. 9.
    Haber, A. H. and Rothstein, B. E. (1969) Radiosensitivity and rate of cell division: “Law of Bergonie and Tribondeau”. Science 163: 1338–1339.PubMedCrossRefGoogle Scholar
  10. 10.
    Haber, A. H. and Schwarz, O. J. (1970) Actions of FUdR on “gamma-plantlets” and unirradiated plants. Plant Physiol. 46 (suppl.): 31.Google Scholar
  11. 11.
    Haber, A. H., Thompson, P. J., Walne, P. L. and Triplett, L. L. (1969) Nonphotosynthetic retardation of chloroplast senescence by light. Plant Physiol. 44: 1619–1628.PubMedCrossRefGoogle Scholar
  12. 12.
    Haber, A. H. and Triplett, L. L. (1970) Testing the specificity of inhibitors of DNA synthesis for growth studies. ASB Bull. 17.: 45.Google Scholar
  13. 13.
    Haber, A. H., Triplett, L. L., Haywood, F. F. and Ward, D. R. (1970) RBE of fast neutrons in growth inhibition: Evidence for a component requiring cell division. Radiat. Res. 44: 446–455.PubMedCrossRefGoogle Scholar
  14. 14.
    Haber, A. H. and Walne, P. L. (1968) Actions of acute gamma radiation on excised wheat leaf tissue. I. Radioresistance of senescence and establishing criteria of death from studies of chlorophyll loss. Radiat. Bot. 8: 389–397.Google Scholar
  15. 15.
    Haber, A. H. and White, J. D. (1960) Action of maleic hydrazide on dormancy, cell division, and cell expansion. Plant Physiol. 35: 495–499.PubMedCrossRefGoogle Scholar
  16. 16.
    Long, T. J. and Haber, A. H. (1965) Growth of embryos on synthetic media after excision from gamma-irradiated (525 kr) and unirradiated wheat grains. Radiat. Bot. 5: 223–231.CrossRefGoogle Scholar
  17. 17.
    Rose, R. J. and Adamson, D. (1969) A sequential response to growth substances in coleoptiles from gamma-irradiated wheat. Planta 88: 274–281.CrossRefGoogle Scholar
  18. 18.
    Schwartz, D. and Bay, C. E. (1956) Further studies on the reversal in the seedling height dose curve at very high levels of ionizing radiations. Amer. Natur. 90: 323–327.CrossRefGoogle Scholar
  19. 19.
    Schwarz, O. J. and Haber, A. H. (1971) The development of pyrimidine nucleoside kinase activities in “gamma-plantlets”. Proc. Assoc. Southern Agr. Workers, 68th. Ann. Conv., p. 201.Google Scholar
  20. 20.
    Setlow, R. B. and Pollard, E. C. (1962) Molecular Biophysics. Addison-Wesley, Reading, Mass. 545 pp.Google Scholar
  21. 21.
    Swanson, C. P. (1957) Cytology and Cytogenetics. Prentice-Hall, Inc., Englewood Cliffs, New Jersey, 596 pp.Google Scholar
  22. 22.
    Walne, P. L. and Haber, A. H. (1968) Actions of acute gamma radiation on excised wheat leaf tissue. II. Immediate lethal dose effects on chloroplast ultrastructure and subsequent re-retardation of normal disintegration in darkness. Radiat. Bot. 8: 399–406.Google Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Alan H. Haber
    • 1
  1. 1.Biology DivisionOak Ridge National LaboratoryOak RidgeUSA

Personalised recommendations