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The Antileprosy Agent Clofazimine (B.663) in Macrophages: Light, Electron Microscope and Function Studies

  • M. L. Conalty
  • A. G. Jina
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)

Abstract

In 1957 in a communication from these laboratories the remarkable antimycobacterial activity of B.663, 3-(P.-chloroanilino)-10-(P.-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine, was first described (1). B.663, now known as Clofazimine, forms the active component of the antileprosy preparation Lamprene (Geigy).

Keywords

Mesenteric Lymph Node Phagocytic Activity Dense Body Buruli Ulcer Electron Microscope Finding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • M. L. Conalty
    • 1
  • A. G. Jina
    • 1
  1. 1.Laboratories, Medical Research Council of Ireland Trinity CollegeDublinIreland

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