Advertisement

The Fine Structure and Peroxidase Activity of Resident and Exudate Peritoneal Macrophages in the Guinea Pig

  • W. T. Daems
  • P. Brederoo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)

Abstract

The morphology, function, and kinetics of mononuclear phagocytes are usually studied in peritoneal macrophages obtained from experimentally induced peritoneal exudates. Although it has been convincingly demonstrated that most of the mononuclear phagocytes present in peritoneal exudates are monocytes deriving from the peripheral blood, it cannot be entirely excluded that a probably varying proportion of the mononuclear phagocytes present in the peritoneal exudates may be resident peritoneal macrophages, i.e. cells already present in the peritoneal cavity.

Keywords

Peritoneal Cavity Alveolar Macrophage Nuclear Envelope Peritoneal Macrophage Mononuclear Phagocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Hirsch, J.G. and M.E. Fedorko, “Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetroxide and ‘postfixation’ in uranyl acetate”, J. Cell Biol. 38, 615, 1968.PubMedCrossRefGoogle Scholar
  2. 2.
    Novikoff, A.B. and S. Goldfischer, “Visualization of peroxisomes (microbodies) and mitochondria with diaminobenzidine”, J. Histochem. Cytochem. 17, 675, 1969.PubMedCrossRefGoogle Scholar
  3. 3.
    Fedorko, M.E. and J.G. Hirsch, “Structure of monocytes and macrophages”, Sem. Hematol. 7, 109, 1970.Google Scholar
  4. 4.
    Daems, W. Th. and P. Brederoo, “The fine structure of mononuclear phagocytes as revealed by freezeetching”. In: Mononuclear phagocytes (R. van Furth, ed.) p. 29. Blackwell Scientific Pubications Oxford and Edinburgh, 1970.Google Scholar
  5. 5.
    Daems, W. Th. and P. Brederoo, in preparation.Google Scholar
  6. 6.
    de Duve, C., “The lysosome in retrospect”. In: Lysosomes in biology and pathology (J.T. Dingle and H.B. Fell, eds.). 1, 3. North-Holland Publ. Co., Amsterdam-London, 1969.Google Scholar
  7. 7.
    Leake, E.S. en E.R. Heise, “Comparative cytology of alveolar and peritoneal macrophages from germfree rats”. In: The reticuloendothelial system and atherosclerosis (N.R. Di Luzio and R. Paoletti, eds.). p.133 Plenum Press, New York, 1967.Google Scholar
  8. 8.
    Daems, W. Th., E. Wisse and P. Brederoo, “Electron microscopy of the vacuolar apparatus”. In: Lysosomes in biology and pathology (J.T. Dingle and H.B. Fell, eds.) 1, 64. North-Holland Publ. Co., Amsterdam-London, 1969.Google Scholar
  9. 9.
    Carr, I. “Lysosome formation and surface changes in stimulated peritoneal cells”, Z. Zellf orsch. 89, 328, 1968.CrossRefGoogle Scholar
  10. 10.
    Hruban, Z. and M. Rechcigl, Jr., “Microbodies and related particles: morphology, biochemistry, and physiology”. In: International Review of Cytology (G.H. Bourne and J.F. Danielli, eds.). Suppl. 1. Academic Press, New York and London, 1969.Google Scholar
  11. 11.
    Daems, W. Th., E. Marani and P. Brederoo, unpublished observations, 1970.Google Scholar
  12. 12.
    Gee, J.B.L., C.L. Vassallo, P. Bell, J. Kaskin, R.E. Basford and J.B. Field, “Catalase-dependent peroxidative metabolism in the alveolar macrophage during phagocytosis”, J. clin. Invest. 49, 1280, 1970.PubMedCrossRefGoogle Scholar
  13. 13.
    van Furth, R. and Z.A. Cohn, “The origin and kinetics of mononuclear phagocytes”, J. exp. Med. 128, 415, 1968.PubMedCrossRefGoogle Scholar
  14. 14.
    Leder, L.-D., “Der Blutmonocyt. Morphologie-Herkunft-Funktion und prospektive Potenz-Monocytenleukämie”. In: Experimentelle Medizin, Pathologie und Klinik (R. Hegglin, u.a. Hrsg.). Band 23. Springer-Verlag, Berlin-Heidelberg-New York, 1967.Google Scholar
  15. 15.
    Brederoo, P. and W. Th. Daems, “Submicroscopic cytology of guinea pig peritoneal exudates. I. The heterogeneity of the granules of neutrophilic granulocytes”. In: Microscopie électronique 1970. Résumés du 7e congrès international de microscopie électronique, Grenoble (P. Favard, ed.). 3, 541. Société Française de Microscopie Electronique, Paris, 1970.Google Scholar
  16. 16.
    Undritz, E., “Die Peroxydasereaktionen und ihre praktische Bedeutung”. In: Zyto-und Histochemie in der Hämatologie (H. Merker, ed.). p. 193. Springer-Verlag, Berlin-Göttingen-Heidelberg, 1963.Google Scholar
  17. 17.
    Daems, W. Th. and P. Brederoo, “Submicroscopic cytology of guinea pig peritoneal exudates. II. The peroxidase activity of the monocytes”. In: Microscopie électronique 1970. Résumés du 7e congrès international de microscopie électronique, Grenoble (P. Favard, ed.). 3, 543. Société Française de Microscopie Electronique, Paris, 1970.Google Scholar
  18. 18.
    van Furth, R., J.G. Hirsch and M.E. Fedorko, “Morphology and peroxidase cytochemistry of mouse promonocytes, monocytes, and macrophages”, J. exp. Med. 132, 794, 1970.PubMedCrossRefGoogle Scholar
  19. 19.
    Langevoort, H.L., Z.A. Cohn, J.G. Hirsch, J.H. Humphrey, W.G. Spector and R. van Furth, “The nomenclature of mononuclear phagocytic cells. Proposal for a new classification”. In: Mononuclear Phagocytes (R. van Furth, ed.). p. 1. Blackwell Scientific Publications, Oxford and Edinburgh, 1970.Google Scholar

Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • W. T. Daems
    • 1
  • P. Brederoo
    • 1
  1. 1.Laboratory for Electron MicroscopyUniversity of LeidenThe Netherlands

Personalised recommendations