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Sequence of Events Leading to the Metabolic Stimulation in PMN Leucocytes during Phagocytosis

  • F. Rossi
  • P. Patriarca
  • D. Romeo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)

Abstract

The most dramatic changes induced by phagocytosis in PMN leucocytes are: 1) increase of oxygen uptake, insensitive to cyanide, rotenone, Antimicin A and amytal; 2) increase of H2O2 production; 3) increase of glucose oxidation through the HMP pathway (1–8). Similar changes are induced by treatment of leucocytes with surfactants (9,10) or antileucocyte antibodies (11).

Keywords

Oxygen Uptake NADPH Oxidase Pyridine Nucleotide NADH Oxidation NADH Oxidase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • F. Rossi
    • 1
  • P. Patriarca
    • 1
  • D. Romeo
    • 1
  1. 1.Istituto di Patologia GeneraleUniversità di TriesteTriesteItaly

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