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Possible Participation of Serum-Complement in the Intracellular Killing of E. Coli

  • Jörg Menzel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)

Abstract

Complement (c) was detected in 1889 by its bactericidal activity against gram-negative bacteria (1). In 1903 (2), it was discovered that C also had an opsonizing effect on bacteria, even if they were resistant to the bactericidal activity. Optimal opsonization was obtained when the third component of C was activated and attached to the bacterial surface (3) whereas for the bactericidal activity all nine components were required (4,5,6).

Keywords

Bactericidal Activity Cover Slip Viable Bacterium Bacterial Surface Intracellular Killing 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • Jörg Menzel
    • 1
  1. 1.DFG-Forschungsgruppe RotherMax-Planck-Institut für ImmunbiologieFreiburgGermany

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