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Function Studies of the Spleen Using Radioactive-Labeled and Heat-Denatured Erythrocytes and their Clinical Value

  • J. Fischer
  • R. Wolf
  • A. León
  • H. Mundschenk
  • A. Hromec
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)

Abstract

The RES as an especially active, functionally versatile, and very extended system has its most important concentration of tissue in the spleen. Till now it was possible only to investigate this organ by cytological and histological methods. Clinical function tests of the spleen were completely unknown until recently. Such investigations have now become possible by labeling the blood cells with gamma-emitting radioisotopes and the development of external counting techniques.

Keywords

Chronic Myeloid Leukemia Acute Leukemia White Pulp Sequestration Index Large Spleen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Mundschenk, H., Fischer, J., and Wolf, R., Aufbau und Arbeitsweise eines 12-Kanalfuntionsmess — Standes zur Erfassung und Auswertung schnell ablaufender hämodynamischer Vorgäng. Int. J. Appl. Rad. Isot. 21 (1970), 199.CrossRefGoogle Scholar
  2. 2.
    Fischer, J., Wolf, R., Mundschenk, H., Léon, A., and Hromec, A. Clincial importance of the functional examination of the spleen using 51-Cr-labeled red cells denatured by heat; experience on 4000 subjects. Dynamic Studies with Radioisotopes in Clinical Medicine and Research, Symposium IAEA Rotterdam, 31 August — 4 September 1970.Google Scholar
  3. 3.
    Teitel, P., Disk-sphere transformation and plasticity alteration of the red blood cells. Nature (London) 206 (1956), 409.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • J. Fischer
    • 1
  • R. Wolf
    • 1
  • A. León
    • 1
  • H. Mundschenk
    • 1
  • A. Hromec
    • 1
  1. 1.Division of Hematology, I. Medical ClinicPolyclinic of the University of MainzGermany

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