Advertisement

Function and Importance of the RES during Perfusion of the Liver

  • W. E. Zimmermann
  • K. H. Rehfeld
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)

Abstract

Conservation of the liver and maintaining the integrity of the RES cells becomes of particular importance in temporary extracorporal homologous or heterologous liver substitution in the treatment of hepatic coma and in bridging rejection crises after transplantation of organs. Since the success of the given therapeutic possibilities depends largely on the function of the RES cells and particularly on their detoxicating properties, we have set ourselves the task of investigating the phagocytic activity of the RES cells in the liver during conservation and prolonged perfusion.

Keywords

Phagocytic Activity Reticuloendothelial System Perfusion Medium Hepatic Coma Phagocytic Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Biozzi, G., B. Benacerraf, and B. N. Halpern: Quantitative study of the granulopectic activity of the reticuloendothelial system; Brit. J. Exp. Pathol. 34:441, 1953.Google Scholar
  2. Flemming, K.: Pharmacological stimulation and depression of the phagocytic function of the RES; The reticuloendothelial system and artherosclerosis. N. R. Di Luzio and R. Paoletti, eds., New York, Plenum Press, 1967.Google Scholar
  3. Miller, L. L., C. G. Bly, M. L. Watson, and W. F. Bale: The dominant role of the liver in plasma protein synthesis. A direct study of the isolated perfused rat liver with the aid of lycine E-C14; J. Exp. Med. 94:431, 1951.PubMedCrossRefGoogle Scholar
  4. Zimmermann, W. E., M. Kessler, G. Lemperle, D. Seitz, and R. Dierkesmann: The avoidance of primary hypoxic damage during liver preservation by perfusion with Hb-free solution; Transplantation Proc., Vol. I, No. 3:819, 1969.Google Scholar
  5. Zimmermann, W. E., P. Bannert, G. Knote, and K. H. Mittermayer: Funktionelle und biochemische Veränderungen des reticuloendothelialen Systems der Leber beim Verbrennungsschock und deren mögliche Auswirkung auf die Infektion; in: Verbrennung skrankheit, Fortischritte in Klinik und Forschung; Schattauer-Verlag, Stuttgart — New York 1969, p. 35.Google Scholar

Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • W. E. Zimmermann
    • 1
  • K. H. Rehfeld
    • 1
  1. 1.Department of SurgeryUniversity of FreiburgFreiburgGermany

Personalised recommendations