Bradykinin and Catecholamines Release from the Adrenal Medulla of the Cat: A Possible Indirect Reflex Mechanism

  • D. Della Bella
  • G. Benelli
  • A. Gandini
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)


The analysis of the experimental results of numerous authors (Vogt, 1965; Robinson, 1967; Staszewska and Vane, 1967; Lewis and Reit, 1966; Comline et al., 1968; Della Bella and Benelli, 1968) who studied the relationship between bradykinin and adrenal glands after the experiments of Lecomte et al. (1961) and of Feldberg and Lewis (1964; 1965), leads us to consider that the problem of the release of catecholamines elicited by bradykinin is notably complex certainly more complex than it appeared initially. We think that further investigations are necessary in order to obtain a satisfactory interpretation for all the experimental data recorded during the above mentioned studies, such as the different sensitivity of the various animal species to bradykinin, the quantitative differences within the same animal species observed both “in vivo” and “in vitro” on the isolated perfused gland, the qualitative differences observed in the course of the pharmacological analysis.


Adrenal Gland Adrenal Medulla Superior Cervical Ganglion Nervous Branch Catecholamine Release 
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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • D. Della Bella
    • 1
  • G. Benelli
    • 1
  • A. Gandini
    • 1
  1. 1.Research Laboratories ZAMBON S.p.A.Bresso-MilanItaly

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