Some Actions of Bradykinin and Related Peptides on Autonomic Ganglion Cells

  • W. B. Haefely
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)


The stimulant action of bradykinin and angiotensin on cells of autonomic ganglia has been described by Lewis & Reit (l965), Haefely, Hürlimann & Thoenen (1966) and Trendelenburg (1966). This paper briefly describes recent results obtained with these two peptides and with the endecapeptides eledoisin and physalaemin on the superior cervical ganglion of the cat using electrophysiological techniques.


Superior Cervical Ganglion Autonomic Ganglion Cervical Sympathetic Trunk Chronic Denervation Ganglionic Transmission 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. De Groat W.O., Volle R.L.: The actions of catecholamines or transmission in the superior cervical ganglion of the cat. J.Pharm.exp.Ther. 154, 1–13, 1966a.Google Scholar
  2. De Groat W.C., Volle R.L.: Interactions between the catecholamines and ganglionic stimulating agents in sympathetic ganglia. J.Pharm.exp.Ther. 154, 200–215, 1966b.Google Scholar
  3. Haefely W., Hürlimann A. & Thoenen H.: The effect of bradykinin and angiotensin on ganglionic transmission. in: Erdos E.G., Back N. & Sicuteri F. (ed.): Hypotensive peptides. 314–328, Springer, New York, 1966.CrossRefGoogle Scholar
  4. Haefely W., Hürlimann A. & Thoenen H.: Wirkungen von Nikotin, DMPP, TMA, Amphetamin und KCl auf das Demarkationspotential des Ganglion cervicale superius and die ganglionäre Transmission. Helv.Physiol.Pharmacol.Acta 25, CR 418–419, 1967.Google Scholar
  5. Haefely W.E.: Effects of catecholamines in the cat superior cervical ganglion and their postulated rôle as physiological modulators of ganglionic transmission. Progress in Brain Research 31, 61–72, 1969.PubMedCrossRefGoogle Scholar
  6. Lewis G.P. and Reit E.: The action of angiotensin and bradykinin on the superior cervical ganglion of the cat. J.Physiol. 179, 558–555, 1965.Google Scholar
  7. Trendelenburg U. & Jones A.: Facilitation of ganglionic responses after a period of preganglionic stimulation. J.Pharm.exp.Ther. 147, 330–335, 1965.Google Scholar
  8. Trendelenburg U.: Observations on the ganglion-stimulating action of angiotensin and bradykinin. J.Pharm.exp.Ther. 154, 418–425, 1966.Google Scholar

Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • W. B. Haefely
    • 1
  1. 1.Department of Experimental MedicineF. Hoffmann-La Roche Ltd.BaselSwitzerland

Personalised recommendations