Abstract
Several workers have observed that under certain conditions kinins, although acting directly on blood vessels causing vasodilatation to produce hypotension, sometimes increase arterial blood pressure as well. Croxatto, Belmar, Pereda and Labacea (1962) reported such an effect when bradykinin was injected into rats with low blood pressure. These authors concluded that the pressor response was not wholly due to the release of catecholamines since it still occurred after adrenalectomy. In rabbits and in rats treated with guanethidine, however, Lecomte, Troquet and Cession-Fossion (1961), observed that the pressor response to bradykinin was abolished after removal of the suprarenal glands.
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Lewis, G.P. (1970). Peptides and the Sympathetic Nervous System. In: Sicuteri, F., e Silva, M.R., Back, N. (eds) Bradykinin and Related Kinins. Advances in Experimental Medicine and Biology, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3198-8_70
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DOI: https://doi.org/10.1007/978-1-4684-3198-8_70
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